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Prof. Dr.

August Böck

Year of election: 1988
Section: Microbiology and Immunology
City: Munich
Country: Germany

Research

August Böck ist Mikrobiologe mit den Forschungsschwerpunkten prokaryontische Molekularbiologie und mikrobielle Physiologie. Mit einer Kombination von genetischen und biochemischen Methoden hat er Mechanismen der Regulation des fermentativen Stoffwechsels gramnegativer Bakterien aufgeklärt und auch die grundlegenden Eigenschaften des Proteinsyntheseapparats von Archaeen charakterisiert. Zu den Höhepunkten seines wissenschaftlichen Schaffens zählen weiterhin die Entdeckung aller Komponenten, die an der Biosynthese der 21. proteinogenen Aminosäure Selenocystein und ihrer Insertion in Selenoproteine beteiligt sind und die Beschreibung der Synthese und des Einbaus eines katalytisch aktiven Metallzentrums in Apoproteine. 

August Böck is a microbiologist working in the special fields of prokaryotic molecular biology and microbial physiology. By using a combination of genetic and biochemical approaches he elucidated the mechanisms involved in the control of fermentative metabolism from gram negative bacteria and he described the basic properties of the protein synthesis machinery from archaea. Highlights of his scientific achievements are the identification and biochemical characterisation of all components involved in the biosynthesis of the 21. proteinogenic amino acid selenocystein and its incorporation into selenoproteins and the description of the complex mechanisms of synthesis and insertion of a catalytically active metal centre into proteins.

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