Leopoldina Menü

Leopoldina Home


List of Members | Expert Search

Search among the members of the Leopoldina for experts in specific fields or research topics. After entering a name in the "Name" field, click on "Search" to go directly to a member profile. With the input and selection in the fields "City" and „Country", you can limit your search locally or regionally, or target specific sections of the Leopoldina. Alternatively or in combination a full-text search is possible for all member profiles - use the upper input field. The use of operators like AND, NOT or * is permitted in the full-text search. For example, you may search for "genetics" or "*genet*" to get results with "genetic" or "molecular genetics". For a new search please click on the following link or use the full-text search in the right column.

New Search

Prof. Dr.

Franz Oesch

Year of election: 1999
Section: Physiology and Pharmacology/Toxicology
City: Wackernheim
Country: Germany
CV Franz Oesch - Englisch (pdf)


Hauptarbeitsgebiete: Isolierung und Charakterisierung der bei der metabolischen Aktivierung potentieller Kanzerogene beteiligten Enzyme aus verschiedenen Spezies (z. B. mikrosomale Epoxidhydrolase, Dihydrodioldehydrogenase, Glutathion-S-Transferasen; Isolation, physikochemische und biochemische Charakterisierung solcher Enzyme, Untersuchungen zum Einfluss dieser Enzyme auf die Kontrolle reaktiver Stoffwechselprodukte); Mutagenität (quantitative Erfassung des Einflusses verschiedener Enzyme auf die Kontrolle reaktiver Stoffwechselprodukte); Testsysteme und ihre Aussagekraft; Studium der metabolischen Aktivierung (u. a. von Metaboliten des Benzo(a)pyrens); Regulation der Aktivität von Cytochrom-P-450-Isoenzymen (spezifische Phosphorylierung, Einfluss verschiedener Nahrungskomponenten); Kompartimentierung von Zellen und deren Konsequenzen für gentoxische Risiken; biochemische Basis der Kanzerogenese (neue Wege des Metabolismus, neue karzinogene Metaboliten; Veränderung der Expression kanzerogenmetabolisierender Enzyme; Auslösung von Krebs durch nicht-gentoxische Stoffe, u. a. Lipidsenker; Studium von Zellmembrankomponenten, die die normale Zellproliferation kontrollieren)


  • since 1981 Professor (C4) of Pharmacology and Toxicology, University of Mainz, Germany
  • 1983-2004 Director, Institute of Toxicology, University of Mainz, Germany
  • 1981-1983 Chairman, Department of Molecular Pharmacology, University of Mainz, Germany
  • 1974-1981 Professor (C3) of Pharmacology and Toxicology; Head, Section on Molecular Pharmacology, University of Mainz, Germany
  • 1973 Habilitation at the University Basel, Switzerland; PD for Pharmacology and Toxicology, University of Basel, Switzerland
  • 1972-1974 Senior Research Associate, Department of Pharmacology, Biocenter of the University of Basel, Switzerland
  • 1969-1971 Fellow of the Visiting Program of the US Health Service, NIAMD, National Institutes of Health, Bethesda, USA
  • 1965-1969 Junior (65-66), then Senior (66-69) Assistant at the University of Fribourg, Switzerland
  • 1969 Promotion an der Universität Fribourg, Switzerland; Ph.D., University of Fribourg, Switzerland
  • 1961-1969 Studies of Chemistry and Biology at the University Fribourg, Switzerland


  • 2003-2004 Chairman of the Research Group „Susceptibility factors of tumorigenesis“
  • 1996-2002 Chairman of the Center Grant „Organ and cell type specificity of tumorigenesis“
  • 1984-1995 Chairman of the Center Grant SFB 302 „Control factors of tumorigenesis“

Honours and Memberships

  • 2012 Poulsson Medal and Annual Lecture Award of the Norwegian Society of Pharmacology  and Toxicology
  • 2008 Election to the National Academy of Medicine of France
  • 2002 Salk Lecture, Salk Institute, La Jolla, USA
  • 2000 Werner Heisenberg-Medaille
  • 2000 Gerhard Zbinden Memorial Lecture Award
  • 1999 Prize for Scientific Innovation of the State Rheinland-Pfalz , Germany
  • 1999 Election to the National Academy of Sciences of Germany Leopoldina
  • 1998 Keynote Review, International EAPCCT Congress, Zurich, Switzerland
  • 1998 Keynote Lecture, European Workshop on Drug Metabolism, Kopenhagen, Denmark
  • 1997 IEM Lecture, Karolinska Institute, Stockholm, Sweden
  • 1996 International Union Against Cancer Roll of Honour
  • 1995 MDC-Lecture, Max Delbrück Centrum für Molekulare Medizin, Berlin, Germany
  • 1994 Novum Lecture, Karolinska Institute, Novum-Stockholm, Sweden
  • 1993 International Society for the Study of Xenobiotics Award
  • 1992 Otto Warburg Memorial Lecture, Berlin, Germany
  • 1992 Election to the Academia Europea
  • 1991 Keynote Lecture, International ISSX Meeting, Amsterdam, Netherlands
  • 1990 German Cancer Price
  • 1989 Prize of the Rheinisch-Westfälische Academy of Sciences, Germany
  • 1986 The Biochemical Society 75th Anniversary Symposium Honoured Lecture, London, UK
  • 1985 GUM Prize
  • 1983 Walter Straub Memorial Lecture, Munich, Germany
  • 1982 Robert Koch Prize
  • 1977 Professor Max Cloetta Prize




Emil-Abderhalden-Str. 35
06108 Halle (Saale)

Phone 0345 - 47 239 - 122
Fax 0345 - 47 239 - 139
E-Mail archiv @leopoldina.org