Profiles of Leading Women Scientists on AcademiaNet.
Search among the members of the Leopoldina for experts in specific fields or research topics.
Image: HIRI
Year of election: | 2013 |
Section: | Microbiology and Immunology |
City: | Würzburg |
Country: | Germany |
Research Interests: RNA molecules as regulators of gene expression, Systematic screens for small RNAs, Deep sequencing technologies
Jörg Vogel has made seminal contributions to our understanding of how cells use noncoding RNA molecules as regulators of gene expression. His research has had its focus on small RNAs in pathogenic bacteria and short and long noncoding RNAs in infected eukaryotic cells. Early contributions include the first systematic screens for small RNAs in E. coli.
Subsequently, he unraveled novel mechanisms elucidating how small RNAs regulate protein synthesis and mRNA decay, and how they recognize mRNAs by conserved short seed pairing domains. More recently, he pioneered the application of emerging deep sequencing technologies to discover regulatory RNAs and their targets on the genome-wide scale in pathogen and host cells.