Leopoldina Menü

Leopoldina Home

Members

List of Members | Expert Search

Search among the members of the Leopoldina for experts in specific fields or research topics. After entering a name in the "Name" field, click on "Search" to go directly to a member profile. With the input and selection in the fields "City" and „Country", you can limit your search locally or regionally, or target specific sections of the Leopoldina. Alternatively or in combination a full-text search is possible for all member profiles - use the upper input field. The use of operators like AND, NOT or * is permitted in the full-text search. For example, you may search for "genetics" or "*genet*" to get results with "genetic" or "molecular genetics". For a new search please click on the following link or use the full-text search in the right column.

New Search

Prof. Dr.

Maode Lai

Year of election: 2011
Section: Pathology and Forensic Medicine
City: Hangzhou
Country: China
CV Maode Lai - Englisch (pdf)

Research

Prof.Lai‘s main research has focused on molecular carcinogenesis of colorectal cancer since 1989. He set up a systematic platform for the molecular pathology and the national cooperative colorectal cancer research group. Now to elaborate EMT and metastasis of colorectal cancer is one of their tasks.They also do Gwas and deep sequencing of tumor samples.

His group confirms that IGFBP7 plays an important role in insulin resistance and is associated with metabolic syndrome,which is a combination of disorders that increase the risk of developing cardiaovascular disease and some malignancies.They are also interested in clarifying the interaction of IGFBP7 and insulin , and the carcinogenesis of related tumors.

In his department the laboratory of molecualr disgnostics carries out molecular tests for personalized medicine and the validity of biomarkers for early diagnosis and liver metastasis of colorectal cancer.

Career

  • since 1995 Director of Department of Pathology, Zhejiang Medical University (now school of medicine ,Zhejiang University), China
  • 1994-1991 Associate Professor
  • 1990 M.D.  Lübeck Medical University, Germany
  • 1989-1990 Lübeck Medical University, Germany
  • 1987-1984 Zhejiang Medical University, China
  • 1982-1978 Zhejiang Medical University, China

Projects

  • 2011-2014 Core Director, Principal Investigator: Mechanism of epithelial- mesenchymal transition in metastasis of colorectal carcinoma(key program). National Natural Science Foundation of China
  • 2010-2012 Organizer of Chinese side, The molecular mechanism of cancers, Sino-German Center (by NSFC and DFG)
  • 2010-2012 Principal Investigator: Regulation mechanism of Reg IV in colorectal tumor, National Natural Science Foundation of China
  • 2009-2013 Core Director, Principal Investigator: Early identification and intervention technique of metabolic syndrome, Ministry of Science and Technology, China
  • 2008-2010 Principal Investigator: Regulation mechanism of IGFBP-rP1 methylation, National Natural Science Foundation of China
  • 2007-2010 Principal Investigator: Development of diagnostic techniques of malignancies, Municipal Bureau of Science and Technology, Zhejiang Province, China
  • 2007-2012 Co-Investigator: Clinical evaluation of tumour biomarkers of common malignancies, Ministry of Science and Technology, China
  • 2007-2010 Co-Investigator: Structure and function of IGFBP-7, “973” project, Ministry of Science and Technology, China
  • 2006-2008 Principal Investigator: Regulation of IGFBP-7 expression and Identification of effective molecules, National Natural Science Foundation of China
  • 2004-2006 Principal Investigator: Identification of C6orf37 homologous sequence in the colonic carcinogenesis, National Natural Science Foundation of China
  • 2001-2003 Principal Investigator: CpG island aberrant methylation in morphologically normal mucosa adjacent to colorectal carcinomas, National Natural Science Foundation of China

Functions

  • since 2010 Chairman, Chinese Society of Pathology
  • since 2010 Chairman, Zhejiang Pathologist Association
  • since 2007 Vice Chairman, Chinese Pathologist Association
  • since 2007 Vice Chairman, National Committee of Medical Education of Basic Sciences, Ministry of Education, China
  • since 2004 Chairman, Zhejiang Society of Pathology
  • since 1999 Vice Chairman, Zhejiang Medical Association

Honours and Memberships

  • 2011 Top specialists of Zhejiang Province, China
  • 2011 First Award of Science and Technology, Zhejiang Province, China
  • 2005 First Award of Science and Technology, Zhejiang Province, China
  • 2004 Second Award of Science and Technology, Zhejiang Province, China
  • 2003 Outstanding Youth Scientist Award, Zhejiang Province, China
  • 1998 Third Award of Science and Technology, Zhejiang Province, China
  • 1994 Third Award of Science and Technology, Zhejiang Province, China
  • 1993 Excellent Teacher of Ministry of Education, China
  • 1990 Huo Yingdong Award for young excellent faculty of China, Ministry of Education, China
  • 1988 Second Award of Science and Technology, Ministry of Health, China
  • 1986 Zhu Kezhen Award for excellent graduate student, China

CONTACT

Leopoldina

Archive


Emil-Abderhalden-Str. 35
06108 Halle (Saale)

Phone 0345 - 47 239 - 122
Fax 0345 - 47 239 - 139
E-Mail archiv @leopoldina.org