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Foto: MPI for Biophysical Chemistry
|Year of election:||2009|
|Section:||Biochemistry and Biophysics|
Our goal is to understand the molecular mechanisms of gene transcription and the principles of genomic regulation in eukaryotic cells. In the past, we have analyzed the structure and function of RNA polymerases, the key cellular enzymes transcribing our genes. We use integrated structural biology to elucidate the three-dimensional architecture of macromolecular complexes.
In addition, we conduct a functional analysis that provides mechanistic insights. Finally, systemic and computational approaches are used to unravel the principles of genomic regulation. Our long-term aim is to bring together molecular biology and systems biology and understand the expression and regulation of the genome.
Image: Max Planck Institute for Biophysical Chemistry
06108 Halle (Saale)
|Phone||0345 - 47 239 - 122|
|Fax||0345 - 47 239 - 139|