Research

Molecular, cellular & clinical topics in thrombosis & hemostasis

Biochemistry, pharmacology, and pathobiochemistry of platelet receptors and signalling by protein kinases A and G (PKA/ PKG) and their substrates

Pathobiochemistry and cross-talk of NO/cGMP-mediated signalling in cardiovascular cells

Structure, function, and cell biology of the Ena/VASP-protein family

Career

• since 2012 University Professor (W3) and Scientific Director, Centrum for Thrombosis and Hemostasis (CTH), University Hospital, University Mainz, Germany
• 1995-2011 University Professor (C4 and Chairman) Institute for Clinical Biochemistry and Pathobiochemistry, University Hospital Würzburg, Germany
• 1989/2000 Board Certification, Internal Medicin, Laboratory Medicin, Hemostaseology
• 1989-1995 Clinical Research Professorship C3/C4 (DFG), Medical University Clinic Würzburg. Germany
• 1985-1989 Resident, fellow, Medical University Clinic, Würzburg, Germany
• 1985 Habilitation (Lecturer) Clinical Biochemistry  (Prof. Dr. E. J. M. Helmreich, Prof. Dr. K. Kochsiek), University of Würzburg, Germany
• 1980-1985 Research Career Development Award (DFG Heisenberg-Fellowship), University of Wurzburg, Germany, University of Texas, Houston, USA
• 1975-1980 Postdoc, Research Associate, Pharmacology, Yale University, New Haven, USA
• 1975 Ph.D., University of Göttingen, Germany
• 1968-1975 Medical School (University of Gottingen) und Biochemical Studies, Brandeis University, Mass., USA

Functions

• since 2012 Full Professor and Scientific Director, CTH Mainz, Germany
• 2006-2013 Coordinator (until 2011) and project leader (until 2013) of the SFB 688 Center Grant “Cardiovascular Cell-Cell Interactions“, Würzburg, Germany
• 2005/2006 Member of the Scientific Board, Medical Faculty, Würzburg, Germany
• 2004-2006 Member of the board of directors, University Hospital Würzburg, Germany
• 2001-2011 Director, Central Laboratory, Clinical Chemistry, University Hospital Würzburg, Germany
• 1996-2004 Founding member/vice-coordinator of the Interdisciplinary Centre for Clinical Research (IZKF), University of Würzburg, Germany
• 1995-1996 Acting Director, Forschungsinstitut f. Molekulare Pharmakologie (Berlin)
• 1993-2004 Founding member, coordinato, vice-coordinator, DFG/SFB 355 Center Grant on heart failure
• 1989-1995 Director (C3/C4-Professorship) of a DFG Clinical Research Group “Cardiovascular Signal Transduction”, University of Würzburg, Germany
• 1985-1999 Founding member, group leader, DFG/SFB 176 Center Grant, signal transduction