Policymakers and society need realistic suggestions on how to make the best use of future opportunities in research and teaching in Germany. In its Report on Tomorrow’s Science, the Leopoldina explains its position on the inherent potential and problems of scientific development in Germany that it regards as being of particular relevance in the medium and long term to the relationship between science, politics and society. The Leopoldina’s first Report on Tomorrow’s Science focuses on rapid technological developments in the biosciences, as well as on the organisational challenges for research and teaching that arise from these breakthroughs.