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UID:725-96@www.leopoldina.org
CLASS: PUBLIC
SUMMARY:Advances on Large Animal Models: Bridging the Gap between Biomedica
 l Research and Clinical Translation
DESCRIPTION:The translation of novel discoveries from basic research to cli
 nical application is a long, often inefficient and costly process. Conseque
 ntly, “translational medicine” became a top priority. Relevant animal model
 s are critically important for the discovery of key disease mechanisms, tar
 gets for medical interventions and subsequent development of new therapies.
  Rodents are the most popular, but findings in rodents are in many disease 
 areas very different from those in human patients. Thus, animal models mimi
 cking human anatomy and physiology more closely are urgently required. In t
 his respect, pigs, small ruminants and rabbits are excellent candidates. CO
 ST Action BM1308 “Sharing Advances on Large Animal Models (SALAAM)” was est
 ablished to (i) share technical information and further improve technology 
 for the development of tailored large animal models; (ii) establish and val
 idate standardized phenotyping protocols; (iii) create a database of existi
 ng models, standardized tissue samples, and validated phenotypic assays; an
 d (iv) develop concepts for the ethical evaluation of experiments with larg
 e animals, including involvement of the regulatory authorities. The confere
 nce will include the latest developments in genetic engineering/gene editin
 g of large animal models and demonstrate their translational value for spec
 ific disease areas and for xenotransplantation. Viewpoints from different s
 takeholders, including scientists, clinicians, pharmaceutical industry and 
 biotech companies, health care systems, patients, and policy makers and fun
 ding agencies will be taken into account. In addition, rational frameworks 
 to evaluate experiments with large animal models by weighing the scientific
  and ethical arguments will be discussed.\n\nFurther Information and Regist
 ration\n\nThere will be an open lecture held by Prof. Dr. Bruno Reichart on
  the topic of heart transplantation on thursday, 28 september. Please regis
 ter via e-mail to: salaam@genzentum.lmu.de. Registration closes on Monday, 
 31 July.\n\nKontakt\n\nProf. Dr. Anne Navarrete SantosMedizinische Fakultät
 , Institut für Anatomie und ZellbiologieMartin Luther Universität Halle-Wit
 tenbergTel.: 0345-5571718E-Mail: a.navarrete-santos@medizin.uni-halle.de
LOCATION:Halle (Saale)
DTSTAMP:20251112T170935Z
DTSTART:20170928T070000Z
DTEND:20170929T153000Z
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