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UID:700-96@www.leopoldina.org
CLASS: PUBLIC
SUMMARY:[Cancelled] Next Generation Environmentally Friendly Antibiotics
DESCRIPTION:Resistance to antibiotics is a severe problem in contemporary m
 edicine. Many antibiotics inhibit protein biosynthesis by hampering the rib
 osome function. Structures of bacterial ribosomes in complex with these ant
 ibiotics illuminated common pathways of antibiotics inhibitory action, but 
 not the species-specific diversity in infectious-diseases susceptibility.\n
 \nRecent structural studies on ribosome from a multi-resistant pathogenic b
 acterium and careful comparisons to ribosomes from non-pathogenic bacteria 
 revealed novel structural motifs, essential to protein biosynthesis but not
  located in the primary ribosomal active sites, hence no mechanism for modi
 fication leading to resistance of these sites is currently known. These led
  to the design of antibiotics with desired properties that can be optimized
  in terms of their chemical properties, toxicity and penetration, alongside
  species-specificity, thus preserving the microbiome, as well as in terms o
 f bio degradability, thus reducing the ecological hazards caused by the spr
 ead of the current antibiotics’ metabolites.\n\nPicture: Photographee.eu - 
 fotolia\n\nContact\n\nDr. Katja PatzwaldScientific OfficerFon.: 030 - 203 8
 997 - 431E-Mail: katja.patzwaldt@leopoldina.org\n\nNotice\n\nThe lecture is
  cancelled.\n\nLinks\n\nMember profile of Ada Yonath 
LOCATION:Berlin
DTSTAMP:20251112T170935Z
DTSTART:20180508T160000Z
DTEND:20180508T180000Z
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