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Potential Applications

Potential Applications

Picture: ssilver - fotolia.com

It seems that CRISPR/Cas9 can be used in all organisms. The technique has raised hopes for possible applications in medicine, animal breeding, biotechnology and crop research. Using CRISPR/Cas9, genetic modification can be used to research diseases, improve the food supply, cure hereditary diseases, find new ways of fighting cancer and HIV, and breed more resilient animals and crops. Suddenly, everything seems possible.

Applications in medicine

Researchers have modified a gene in human immune cells to make the cells immune against the HI virus. Modified blood stem cells could also be used to treat blood disorders. Goats could be bred that are less prone to disease and pigs whose organs could be used for transplantation. Mosquitoes that transmit infectious diseases such as malaria could be genetically modified to become resistant or be wiped out. CRISPR/Cas9 has already been adopted in research labs around the world to produce modified cell lines and precisely activate or inactivate genes to research the mechanisms of disease.

Leopoldina President Jörg Hacker about hopes in medicine (German)

Application in crop breeding

CRISPR/Cas9 is also being used in crop research. Strains of rice and wheat are being genetically modified to make them more resilient against pests. Genetic engineers are working on making crops resilient to climate change, on wheat that contains less gluten and fruit with higher levels of vitamins. CRISPR/Cas9 can modify the DNA of crops much more quickly and precisely than the standard random mutagenesis and crossbreeding methods used in conventional breeding until now.

CONTACT

Leopoldina

Dr. Henning Steinicke

Scientific Officer, Department Science - Policy - Society

Phone 0345 - 47 239 - 864
Fax 0345 - 47 239 - 839
E-Mail henning.steinicke @leopoldina.org

CONTACT

Leopoldina

Dr. Johannes Fritsch

Head of Office of the Joint Committee for the Handling of Security-Relevant Research

Phone 0160 9121 2676
Fax 030 - 203 8997 - 409
E-Mail johannes.fritsch @leopoldina.org

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Leopoldina

Caroline Wichmann

Head of Department Press and Public Relations

Phone 0345 - 472 39 - 800
Fax 0345 - 472 39 - 809
E-Mail caroline.wichmann @leopoldina.org

The opportunities and...