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UID:998-96@www.leopoldina.org
CLASS: PUBLIC
SUMMARY:Bacterial Methylomes
DESCRIPTION:English AbstractNobel laureate Sir Richard J. Roberts (UK/USA) 
 focuses in his presentation on bacterial DNA methyltransferases (MTases), w
 hich are best known as orphan enzymes such as the Dam methylase of E. coli 
 or as components of restriction-modification (RM) systems. Until recently, 
 rigorously determining the specificity of MTases has been a tedious process
 . When they were components of Type II restriction systems it has been assu
 med that the MTases would have the same specificity as the cognate restrict
 ion enzyme. For Type I and Type III RM systems specificity determination wa
 s rarely attempted.  With the advent of SMRT sequencing from Pacific Biosci
 ences this situation has changed dramatically. Now it has become very simpl
 e to determine MTase recognition sequences both for individual MTases clone
 d in plasmids and also for whole bacterial genomes. This offers new insight
 s into the functioning of bacteria and has led to the discovery of many nov
 el MTases with unexpected properties. A new door on bacterial life has been
  opened and raises many questions.  \n\nSir Richard J. Roberts\n\n   ist Ch
 ief Scientific Officer an den New England Biolabs, Beverly, Massachusetts. 
 Er hat 1993 gemeinsam mit Phillip Allen Sharp den Nobelpreis in Physiologie
  oder Medizin „für ihre Identifizierung des diskontinuierlichen Aufbaus ein
 iger Erbanlagen von Zellorganismen“ erhalten.\n\nKontakt\n\nDr. Jan NissenN
 ationale Akademie der Wissenschaften LeopoldinaTel. (0)345 - 47239 - 834jan
 .nissen@leopoldina.org\n\nWeitere Informationen und Anmeldung\n\nDer Vortra
 g wird auf Englisch gehalten. Die Teilnahme ist kostenlos. Um Anmeldung bis
  zum 23. Mai wird gebeten. Anmeldung
LOCATION:Halle (Saale)
DTSTAMP:20251112T170935Z
DTSTART:20140526T163000Z
DTEND:19700101T190000Z
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