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Year of election: | 2007 |
Section: | Chemistry |
City: | Aachen |
Country: | Germany |
The main objective of Dieter Enders’ research is the development of selective new methods in the area of asymmetric synthesis and their application in the synthesis of natural and bioactive compounds. Pheromones, flavours, alkaloids, polyketides, macrolides, sphingolipids and carbohydrates can be synthesized with high diastereo- and enantioselectivity by employing metalated chiral hydrazones, α-aminonitriles, lactams and sulfonates. Another research field is the asymmetric transition metal catalysis with ferrocene and carbene ligands. Nowadays the focus is on the development of new organocatalytic methods where small organic molecules such as the amino acid proline and N-heterocyclic carbenes are used as catalysts under metal-free conditions. Special emphasis is laid on asymmetric organocatalytic domino reactions.