Professor Dr Annette Beck-Sickinger
- Section Chemistry
- Location Leipzig, Germany
- Election year 2012
Research
Annette G. Beck-Sickinger is distinguished for many important contributions in the field of peptide-protein interactions.
One of her major interest includes the investigation of the interactions of peptide/protein ligands with G-protein coupled receptors, their modulation and identification of mechanisms. This has been applied to the development of therapeutic peptides and proteins in the fields of metabolic diseases, tumor therapy and pain research.
Her second field of interest lies in the field of chemical modification of proteins for the identification of novel target proteins, selective immobilization of proteins on surfaces and in the development of novel biomaterials.
One of her major interest includes the investigation of the interactions of peptide/protein ligands with G-protein coupled receptors, their modulation and identification of mechanisms. This has been applied to the development of therapeutic peptides and proteins in the fields of metabolic diseases, tumor therapy and pain research.
Her second field of interest lies in the field of chemical modification of proteins for the identification of novel target proteins, selective immobilization of proteins on surfaces and in the development of novel biomaterials.
Career
- 2009 Guest professor, Vanderbilt University, Nashville, USA
- since 2008 Acting Director, Institut für Biochemie, Universitaet Leipzig
- since 1999 Professor of Biochemistry and Bioorganical Chemistry, Universitaet Leipzig
- 1997-1999 Assistant Professor for Pharmaceutical Biochemistry, Eidgenössische Technische Hochschule (ETH) Zurich
- 1995 Habilitation in Biochemistry, Universitaet Tübingen
- 1992 Research at Rigshospitalet Kopenhagen, Denmark
- 1990-1991 Postdoc at the Biochemistry Laboratory, ETH Zurich
- 1990 Diploma in Biology, Universitaet Tübingen
- 1989 Ph.D. in Organic Chemistry, Universitaet Tübingen
- 1988 Research at Srcipps Clinic & Research Foundation in La Jolla, USA
- 1986 Diploma in Chemistry, Universitaet Tübingen
Functions
- 2018-2021 Chair of the university council, University of Hohenheim
- 2012-2018 Member, Wissenschaftsrat
- since 2012 Member of the university council, University of Hohenheim
- since 2010 Member, Hochschulrat of the Universitaet Leipzig
- 2008-2012 Head of the Fachkollegium „Grundlagen der Biologie und Medizin“, German Research Foundation (DFG)
- 2006-2008 Vice-President, Gesellschaft Deutscher Chemiker (GDCh)
- 2004-2012 Member, Committee of the Gesellschaft Deutscher Chemiker (GDCh)
Projects
- 2013-2017 Project “Ensemble Docking Interrogates Structural Determinants of Ligand-Protein Interactions”
- since 2013 SFB 1052 „Mechanismen der Adipositas“, project „Die Funktion von Y-Rezeptoren bei der Regulation der Nahrungsaufnahme“ (A03) and project „Molekulare Mechanismen der Wirkung von Adipokinen“ (C02)
- 2012-2018 DFG SPP 1623: „Chemoselektive Reaktionen für die Synthese und Anwendung funktionaler Proteine“, project „Selective bioconjugation of proteins in live cells via peptide-directed acyl and alkyl transfer reactions“
- 2009-2021 DFG Transregio TRR 67: „Funktionelle Biomaterialien zur Steuerung von Heilungsprozessen in Knochen- und Hautgewebe - vom Material zur Klinik“, Integriertes Graduiertenkolleg: „Matrixengineering“ (MGK)
- 2006-2015 DFG FOR 630: „Biologische Funktion von Organometallverbindungen“, project „Markierung von Peptidhormonen mit Metallkomplexen für Tumordiagnostik und –therapie“
- 2006-2015 DFG Clinical research group KFO 152: „Atherobesity: Fett und Gefäß“, project „Atherobesity: Molekulare Mechanismen“
Honours and Memberships
- 2023 Richard Willstätter Prize for Chemical Biology, DECHEMA Society for Chemical Engineering and Biotechnology, Frankfurt am Main, German Pharmaceutical Society (DPhG), Society for Biochemistry and Molecular Biology (GBM), Frankfurt am Main, German Chemical Society (GDCh)
- 2019 Vincent du Vigneaud Award, American Peptide Society
- 2018 Albrecht-Kossel-Preis der Gesellschaft Deutscher Chemiker (GDCh)
- 2016 Leipziger Wissenschaftspreis of the Sächsische Akademie der Wissenschaften, the University of Leipzig and the City of Leipzig
- since 2012 Member of the National Academy of Sciences Leopoldina
- since 2009 Member of the Sächsische Akademie der Wissenschaften
- 2009 Gold Medaö of the Max Bergmann-Kreis
- 2008 Sigma Award Lecture, Royal Chemical Society, Netherlands
- 1999 Phönix Wissenschaftspreis
- 1998 Leonidas Zervas Award, European Peptide Society