Professor Dr Michael Peter Manns (✝︎)

Michael Manns acclaimed excellence through many articles in the areas of Internal Medicine, Gastroenterology, Hepatology, Infectiology and Transplantation. These contributions were accomplished during the time he spent at the Free University of Berlin, the Johannes Gutenberg University of Mainz, the Scripps Clinic and Research Foundation, La Jolla, USA, and above all at the Clinic for Gastroenterology, Hepatology and Endocrinology of the Medical School Hannover, which he directed from 1991.
His main focus in research encompassed viral and autoimmune liver diseases, transplantation medicine, mucosal immunology, gastrointestinal oncology, most importantly hepatocellular carcinoma, regenerative medicine, cell therapy as well as clinical pharmacology. He became well known through his investigations on the immunopathogenesis of inflammatory liver diseases, especially in the areas of molecular characterization of hepatocellular autoantigens and through clinical studies for the therapy of viral hepatitis and autoimmune liver diseases. Clinical studies under his jurisdiction led, among others, to the standards for the treatment of acute and chronic hepatitis C. He was identified with the areas of transplantation and regenerative medicine. He and his working group introduced the first clinical programme for hepatocyte transplantation in Germany. Apart from that, he also founded the national competence network on viral hepatitis entitled “Hep-Net” of the BMBF and the German Liver Foundation.