Prof. Dr. Wolf-Dieter Heiss
- Fachbereich Neurowissenschaften
- Ort Köln, Deutschland
- Wahljahr 1999
Forschung
Wolf-Dieter Heiss hat sowohl experimentell als auch klinisch gearbeitet und dabei Ergebnisse der experimentellen Forschung auf die klinische Anwendung übertragen sowie klinische Fragestellungen im Tiermodell untersucht. Die Arbeiten, die nach Ausbildung und Tätigkeit an der Univ. Klinik für Neurologie in Wien und mehreren Auslandsaufenthalten am Max-Planck-Institut in Köln (1978-2005) und an der Klinik für Neurologie (1985-2005) ausgeführt wurden, konzentrierten sich auf die zerebrale Ischämie und den Schlaganfall sowie auf die Entwicklung bildgebender Verfahren zur Untersuchung von Hirnstoffwechsel und –funktion. In Verbindung dieser Arbeitsgebiete erforschte er die Überlebensfähigkeit des Gehirngewebes während Durchblutungsstörungen, die eine entscheidende Grundlage für die Entwicklung von Therapien des Schlaganfalls, z. B. der Thrombolyse, bildeten. Weitere Arbeitsgebiete betrafen Veränderungen unterschiedlicher Stoffwechselparameter bei Hirntumoren und Demenzen, die zur Verbesserung der Diagnose und Therapie dieser Erkrankungen beitrugen, sowie die funktionellen Aktivierungsmuster im Gehirn bei Gesunden und Patienten, die zum Verständnis von Defekten und von Kompensationsmechanismen wichtig sind.
Wolf-Dieter Heiss was involved in experimental and clinical neuroscience and has transferred results from experimental research into clinical application as well as tested clinical questions in animal models. His research activities, which after training and initial work at the Department of Neurology of the University of Vienna and several research appointments abroad were mainly performed at the Max Planck Institute for Neurological Research (1978-2005) and at the Department of Neurology (1985-2005) in Cologne, were concentrated on cerebral ischemia and stroke and on the development of imaging modalities for investigations of brain metabolism and function. With these methods he studied the ability of the brain to survive blood flow disturbances, which became the essential basis for the development of effective therapy of stroke, e. g. thrombolysis. Further topics of research included various metabolic disturbances in brain tumors and in dementias, which improved diagnostic accuracy and treatment strategies, as well as patterns of functional activation in healthy controls and patients, which contributed to the understanding of deficits and of compensatory mechanisms.
Wolf-Dieter Heiss was involved in experimental and clinical neuroscience and has transferred results from experimental research into clinical application as well as tested clinical questions in animal models. His research activities, which after training and initial work at the Department of Neurology of the University of Vienna and several research appointments abroad were mainly performed at the Max Planck Institute for Neurological Research (1978-2005) and at the Department of Neurology (1985-2005) in Cologne, were concentrated on cerebral ischemia and stroke and on the development of imaging modalities for investigations of brain metabolism and function. With these methods he studied the ability of the brain to survive blood flow disturbances, which became the essential basis for the development of effective therapy of stroke, e. g. thrombolysis. Further topics of research included various metabolic disturbances in brain tumors and in dementias, which improved diagnostic accuracy and treatment strategies, as well as patterns of functional activation in healthy controls and patients, which contributed to the understanding of deficits and of compensatory mechanisms.