Prof. Dr. Bernhard Fleckenstein (✝)
- Fachbereich Mikrobiologie und Immunologie
- Ort Erlangen, Deutschland
- Wahljahr 1996
Forschung
Bernhard Fleckenstein hat sich durch seine Beiträge zur Herpesvirus-Onkologie einen Namen gemacht, die er überwiegend am Virologischen Institut der Universität Erlangen-Nürnberg erbracht hat. Dessen Leitung hat er, 1978 von Harvard Medical School kommend, seither kontinuierlich inne. Seine Gruppe klärte die molekulare Struktur von Rhadinoviren (γ2-Herpesviren) auf, entdeckte deren Onkogene und beschrieb die Transformation humaner T-Lymphozyten durch die Viren. Studien zur Transkriptionskontrolle des menschlichen Cytomegalovirus (CMV), ein β-Herpesvirus, führten zur Entdeckung des CMV-Enhancers, der weltweit zur eukaryonten Expressionsklonierung verwendet wird. Bernhard Fleckenstein ist Leiter des Nationalen Referenzzentrums für humane Retroviren und Generalsekretär der neu gegründeten European Society for Virology.
Bernhard Fleckenstein is known for his contributions to herpesvirus oncology that were mostly done in the Institute for Virology of the University of Erlangen-Nürnberg. Coming from Harvard Medical School in 1978, he has been Chairman of this institution since then. His group analyzed the molecular structure of rhadinoviruses (γ2 herpesviruses), detected their oncogenes and described transformation of human T-lymphocytes by these viruses. Studies on the transcription control of human cytomegalovirus (CMV), a β-herpesvirus, led to the detection of the CMV enhancer that is generally used for eukaryotic expression cloning. Bernhard Fleckenstein is directing the National Reference Center for Human Retroviruses and is Secretary General of the newly founded European Society for Virology.
Bernhard Fleckenstein is known for his contributions to herpesvirus oncology that were mostly done in the Institute for Virology of the University of Erlangen-Nürnberg. Coming from Harvard Medical School in 1978, he has been Chairman of this institution since then. His group analyzed the molecular structure of rhadinoviruses (γ2 herpesviruses), detected their oncogenes and described transformation of human T-lymphocytes by these viruses. Studies on the transcription control of human cytomegalovirus (CMV), a β-herpesvirus, led to the detection of the CMV enhancer that is generally used for eukaryotic expression cloning. Bernhard Fleckenstein is directing the National Reference Center for Human Retroviruses and is Secretary General of the newly founded European Society for Virology.