Research

François Diederich is an expert in chemical and biological molecular recognition.

In a multi-dimensional approach, his research group deciphers and quantifies weak intermolecular interactions such as aromatic-aromatic and dipolar interactions. The gained insight benefits the structure-based development of nonpeptidic enzyme inhibitors that is pursued in his group, in particular targeting new therapeutic leads against tropical diseases.

Another focus of his research are supramolecular nanosystems, such as switchable receptors, and nano-structured surfaces with guest-hosting properties. François Diederich is a leading scientist in carbon-rich materials, such as fullerenes and acetylenic networks. His work is highly synthesis-driven and characterized by a blend of advanced physical-organic analysis, involving numerous international collaborations.