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Year of election: | 2011 |
Section: | Chemistry |
City: | Basel |
Country: | Switzerland |
Andreas Pfaltz has made himself a name for his seminal contributions in the field of asymmetric catalysis. Most of his research was carried out at the University of Basel, where he is Ordinarius (Full Professor) of Organic Chemistry, and at the Max Planck Institute for Coal research, where he served as director and head of the Section of Homogeneous Catalysis.
The goal of his research in this area is to develop chiral catalysts, which control a chemical reaction is such a way that it leads preferentially to one of two enantiomers (mirror-imaged molecules) with high selectivity. The chiral catalysts developed in his group have found widespread use. Most noteworthy are iridium complexes with nitrogen-phosphorus ligands, which are the first catalysts that allow highly enantioselective hydrogenation of unfunctionalized olefins and, therefore, greatly enhance the scope of asymmetric hydrogenation. In a more recent line of research, he has devised a new mass spectrometric screening method that opens up new possibilities for the discovery and optimization of chiral catalysts.