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Nobel Prize in Chemistry 1987
Year of election: | 1985 |
Section: | Chemistry |
City: | Strasbourg |
Country: | France |
Research Priorities: Supramolecular chemistry, cryptands, cage molecules, ion confinement, self-organisation of matter, adaptive chemistry, artificial photosynthesis
Jean-Marie Lehn is one of the pioneers of “supramolecular chemistry” and described the substance class of cryptands for the first time. In 1987 he and the two US-American chemists Donald Cram and Charles Pedersen were jointly awarded the Nobel Prize in Chemistry for the “development and use of molecules with structure-specific interactions of high selectivity”. The scientists provided essential insights into the transport of ions through cell membranes.
Supramolecular chemistry explores the self-organisation of matter. It concerns intermolecular bonds and the new properties that result from these bonds. Two or more chemical species arrange themselves into a supermolecule through intermolecular interactions. Naturally occurring molecules can take up sodium or potassium ions for example and channel them through biological membranes. The ion inclusion gives the molecule other properties. The field of research is also referred to as host-guest chemistry because it relates to molecular constructions which host molecular guests.
The cryptands developed by Jean-Marie Lehn, organic cage molecules, can form two or more rings and store cations in these cavities. The complexes are readily soluble in water and polar solvents and almost insoluble in non-polar organic solvents. In the chemical industry the compounds are used as transport vehicles and ion exchangers.
In his further career, Jean-Marie Lehn researched the self-organisation and self-recognition of molecular systems at the interface between chemistry and biology, and also the path towards adaptive chemistry. He worked on artificial photosynthesis and the conversion of light into chemical or electrical energy and the storage of solar energy.