Research

Michael Manns has acclaimed excellence through many articles in the areas of Internal Medicine, Gastroenterology, Hepatology, Infectiology and Transplantation. These contributions were accomplished during the time he spent at the Free University of Berlin, the Johannes Gutenberg University of Mainz, the Scripps Clinic and Research Foundation, La Jolla, USA and above all at the Clinic for Gastroenterology, Hepatology and Endocrinology of the Medical School Hannover which he has directed since 1991.
His main focus in research encompasses viral and autoimmune liver diseases, transplantation medicine, mucosal immunology, gastrointestinal oncology, most importantly hepatocellcular carcinoma, regenerative medicine, cell therapy as well as clinical pharmacology. He has become well known through his investigations on the immunopathogenesis of inflammatory liver diseases, especially in the areas of molecular characterization of hepatocellular autoantigens and through clinical studies for the therapy of virus hepatitis and autoimmune liver diseases. Clinical studies under his jurisdication led among others to the present standards for the treatment of acute and chronic hepatitis C. He is identified with the areas of transplantation and regenerative medicine. He and his working group introduced the first clinical programme for hepatocyte transplantation in Germany. Apart from that he also founded the national competence network on viral hepatitis entitled “Hep-Net” of the BMBF and the German Liver Foundation.